Chemical Studies on the Gonadotropic Hormone of Pregnant Mare Serum
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The Effects of Gonadotropic Hormones in the Treatment of Experimental Tuberculosis
Experimental tuberculosis in rabbits and guinea pigs was favorably influenced by the administration of antuitrin-S, pregnant mare serum, and, to a lesser extent, follutein. No retardation of disease was obtained by the use of either anterior pituitary extract or emmenin. The results suggest that the gonadotropic hormone may be a factor in the temporary amelioration of symptoms observed in tuber...
متن کاملConcentration of the Gonadotropic Hormone in Pregnant Mare's Serum
The gonadotropic hormone of the blood of the pregnant mare has been greatly concentrated by adsorption on active aluminum hydroxide followed by elution. The preparations so obtained gave demonstrable gonadotropic effects within 100 hours in 21 day old female mice following three subcutaneous injections of 0.001 mg. in 1 cc. of physiological saline. As is well known, other gonadotropic substance...
متن کاملMolecular structures of glycoprotein hormones and functions of their carbohydrate components.
The glycoprotein hormones discussed in this review belong to a family of homologous proteins which are secreted by the anterior pituitary gland of all vertebrates as well as by placental cells ofprimates and equids. The pituitary glycoprotein hormones include follitropin (follicle-stimulating hormone, FSH) and lutropin (luteinizing hormone, LH), essential regulatory elements of ovary and testis...
متن کاملAction of Ketene on Gonadotropic Hormones*
Ketene has been found to be a highly specific,acetylating agent for aqueous solution of proteins. It reacts only with amino, thiol, and phenolic hydroxy groups (1). Several investigators (24) have shown that the primary amino groups react most rapidly, while the hydroxy groups of tyrosine are acetylated at a much slower rate. The hydroxy groups in carbohydrate radicals of the protein molecule d...
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